Introducing LathMized® NAD⁺ · LNAD⁺
Don’t just ask how much NAD⁺ is in the scoop.
Ask how much
is still
alive.
By “alive,” we mean NAD⁺ that stays functionally intact and enzymatically recognizable — still able to participate in NAD⁺ biology. LNAD⁺ is engineered to preserve it on the way into the cell.
Double-blind
Placebo-controlled
Randomized · N=51
LNAD⁺
targeted entry
+0%
NAD⁺ increase
in 5 days
The NAD⁺ Problem
Circulating NAD⁺
≠
Intracellular NAD⁺
Most NAD⁺ strategies — precursors and IV infusions alike — are judged by a number in the blood. But NAD⁺ biology is compartmentalized. Sirtuins, PARPs and mitochondrial enzymes work inside the cell. Plasma is a transit space.
“
A blood signal is not the same as a cellular mechanism.
Circulating NAD⁺
≠
Intracellular NAD⁺
Compartmentalization matters
The distinction that matters
A label can say NAD⁺.
The molecule can still be a
ghost.
NAD⁺ is not just an ingredient. It is a precision coenzyme — and how it survives the journey to your cells decides whether it can do anything at all.
Present, not functional
Degraded NAD⁺
Chemically present, biologically absent. NAD⁺ that has degraded, inactivated, or become poorly characterized by the time it reaches the cell — on the label, but no longer able to do the work of a coenzyme.
Intact & engaged
Live NAD⁺
/ engaged
Functionally intact and enzymatically recognizable. NAD⁺ that stays biologically measurable and can still participate in NAD⁺ biology inside the cell. This is what LNAD⁺ is engineered to preserve.
LNAD⁺ is engineered to protect NAD⁺ from becoming a ghost — preserving it in its functional, biologically recognizable form.
The Evidence · Renewal-NAD⁺ Trial
Measured inside the cell.
In just
five days.
A short, mechanism-of-action study built to ask one question: did NAD⁺ biology actually change inside the cell?
+
0
%
Increase in intracellular NAD⁺ (icNAD⁺) by Day 6 versus baseline, in the LNAD⁺ arm.
p = 4.13 × 10⁻¹³
treatment × time
−4.5%
placebo, over the same five days
Intracellular NAD⁺
change from baseline, by study day
LNAD⁺
Placebo
Day 0
Day 2
Day 4
Day 6
N = 51
Treated participants
analyzed
analyzed
46–72
Age range of
the cohort
the cohort
23 / 28
LNAD⁺ / placebo
allocation
allocation
5 days
Oral swish-and-
swallow regimen
swallow regimen
How LNAD⁺ Works
Engineered for the journey in.
A physicochemically modulated formulation designed to alter how NAD⁺ behaves — while preserving its native structure.
01
Physicochemical modulation
Alters how NAD⁺ behaves on its way through the body — without altering its native molecular structure.
02
Targeted cellular entry
Designed to support delivery into cells — where NAD⁺ matters most — rather than simply flooding the circulation.
03
Preserved & recognizable
Keeps NAD⁺ functionally intact and enzymatically recognizable, so it can still participate in NAD⁺ biology.
Designed to support increases in
NAD⁺ availability
Metabolic flux
Bioenergetic function
Cellular resilience
Clear Boundaries
What LNAD⁺ is — and what it is not.
The credibility of this work depends on clean boundaries. Here is exactly what the science supports — and what it does not yet.
LNAD⁺ is
An oral, LathMized® NAD⁺ formulation (LNAD⁺).
Studied in a randomized, double-blind, placebo-controlled human trial.
Observed to raise intracellular NAD⁺, with downstream NAD-dependent pathway signals.
Best understood as precision nutritional & metabolic support.
LNAD⁺ is not
A treatment for aging, cardiovascular disease, cancer, addiction, or neurodegeneration.
A substitute for medical care, diagnosis, or clinical endpoints.
The same as flooding the bloodstream, the way IV NAD⁺ does.
A claim to prevent, diagnose, treat, or cure any disease.
“
Mechanism is the bridge between molecule and medicine — not a substitute for clinical endpoints.
Our scientific guardrail
Get in touch
Be among the first to ask the better question.
Have a question about the science, the trial, or LNAD⁺ itself? Our team reads every note — and would love to hear from you.